Warning: SPOILERS for Star Trek: Picard Season 3, Episode 4 – "No Win Scenario"Star Trek: Picard season 3's Changeling storyline has finally answered whether the Borg ever encountered Star Trek: Deep Space Nine's Dominion Founders. The Changelings made a shock return in Picard season 3, episode 3, "Seventeen Seconds", when it was revealed that a rogue schism was behind the theft from Daystrom Station, and the sabotage aboard the USS Titan-A. Commander Seven of Nine (Jeri Ryan) and Jack Crusher (Ed Speelers) unmasked the Changeling saboteur aboard the Titan, and in "No Win Scenario", Seven continues to track the imposter with help from Captain Liam Shaw (Todd Stashwick).
Shaw is aware of the Changelings from the time of the Dominion War in Star Trek: Deep Space Nine, whereas Seven has never encountered one. As the Dominion were forced to withdraw from the Alpha Quadrant prior to the USS Voyager returning home, this isn't surprising. However, Seven is a former Borg drone, and her lack of knowledge about the Dominion and their Changeling Founders definitively answers whether the Borg encountered the Changelings.